Search results for "T-lymphoblasts detection"

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Photoluminescent Detection of Human T-Lymphoblastic Cells by ZnO Nanorods.

2020

The precise detection of cancer cells currently remains a global challenge. One-dimensional (1D) semiconductor nanostructures (e.g., ZnO nanorods) have attracted attention due to their potential use in cancer biosensors. In the current study, it was demonstrated that the possibility of a photoluminescent detection of human leukemic T-cells by using a zinc oxide nanorods (ZnO NRs) platform. Monoclonal antibodies (MABs) anti-CD5 against a cluster of differentiation (CD) proteins on the pathologic cell surface have been used as a bioselective layer on the ZnO surface. The optimal concentration of the protein anti-CD5 to form an effective bioselective layer on the ZnO NRs surface was selected. …

room temperature photoluminescenceT-LymphocytesPharmaceutical Science02 engineering and technologyBiosensing TechniquesT-lymphoblasts detection01 natural sciencesAnalytical Chemistryhemic and lymphatic diseasesDrug Discoveryeducation.field_of_studyNanotubesmedicine.diagnostic_testAntibodies MonoclonalPrecursor Cell Lymphoblastic Leukemia-Lymphoma021001 nanoscience & nanotechnologyFlow CytometryChemistry (miscellaneous)Molecular MedicineNanorodZinc Oxide0210 nano-technologymonoclonal antibody anti-CD5PhotoluminescenceMaterials sciencePopulationchemistry.chemical_elementNanotechnologyZincCD5 AntigensArticleFlow cytometrylcsh:QD241-441Adsorptionlcsh:Organic chemistryCell Line TumormedicineHumansPhysical and Theoretical ChemistryeducationMOLT-4 cell linecluster of differentiation proteins010401 analytical chemistryOrganic Chemistry0104 chemical sciencesNanostructureschemistryCancer cellLuminescent MeasurementsGlassBiosensorzinc oxide nanorodsMolecules (Basel, Switzerland)
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